Piperlongumine

Piperlongumine is a alkaloid , possesses ant-inflammatory, antibacterial, antiangiogenic, antioxidant, antitumor, and antidiabetic activities . Piperlongumine induces ROS, and induces apoptosis in cancer cell lines . Piperlongumine shows anti-cardiac fibrosis activity, suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway. Piperlongumin could be used in the study of migrasome .


Cat. No.: EX-A2925	Purity: >98%

	Chemical structure of Piperlongumine

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
5g	708	in_stock

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Synonyms	Piplartine
CAS No.	20069-09-4
Purity	>98%
Formula	C17H19NO5
Mol Weight	317.3365
Color	White to yellow
State	solid powder
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Karki K, et al. Piperlongumine Induces Reactive Oxygen Species (ROS)-Dependent Downregulation of Specificity Protein Transcription Factors. [2]. Wu X, e,t al. Piperlongumine inhibits angiotensin II-induced extracellular matrix expression in cardiac fibroblasts. J Cell Biochem. 2018 Dec;119(12):10358-10364 [3]. Yan Qin , et al. Pan-cancer analysis identifies migrasome-related genes as a potential immunotherapeutic target: A bulk omics research and single cell sequencing validation. Front Immunol. 2022 Nov 3;13:994828.
CoA	CoA of Piperlongumine

Smiles:	COC1=CC(\C=C\C(=O)N2CCC=CC2=O)=CC(OC)=C1OC


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