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Product Information:

PIM-447 dihydrochloride

PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIM kinase inhibitor.

Cat. No.: EX-A3523    Purity: >98%
Chemical
Chemical structure of PIM-447 dihydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg785In-stock
100mg1185In-stock
250mg1885In-stock
500mg2985In-stock
1g4200In-stock
5g13650Inquire


SynonymsLGH447 dihydrochloride
CAS No.1820565-69-2
Purity>98%
FormulaC24H25Cl2F3N4O
Mol Weight513.383
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Paíno T et al. The novel pan-PIM kinase inhibitor, PIM447, displays dual anti-myeloma and bone protective effects, and potently synergizes with current standards of care. Clin Cancer Res. 2016 Jul 20.
CoACoA of PIM-447 dihydrochloride
Smiles:O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C([C@H]4C[C@@H](N)C[C@@H](C)C4)C=CN=C3.Cl.Cl

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