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Product Information:

PIM-1 Inhibitor 2

PIM1-IN-2 is a potent and ATP competitive Pim-1 inhibitor with a Ki of 91 nM. PIM1-IN-2 targets the ATP-binding kinase hinge region not by forming classical hydrogen bonds[1].

Cat. No.: EX-A14561    Purity: >98%
Chemical
Chemical structure of PIM-1 Inhibitor 2


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg588In-stock
250mg1065In-stock
500mg1495In-stock
1g2172In-stock
5gget quoteInquire


CAS No.477845-12-8
Purity>98%
FormulaC17H11ClN4O
Mol Weight322.748
ColorLight yellow to yellow
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃, 3 years; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Pierce AC, Jacobs M, Stuver-Moody C. Docking study yields four novel inhibitors of the protooncogene Pim-1 kinase. J Med Chem. 2008 Mar 27;51(6):1972-5.

CoACoA of PIM-1 Inhibitor 2
Smiles:C1=CC(=CC=C1C2=C3C=C(C=CC3=NO2)C4=NC(=NC=C4)N)Cl

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