PI4KβPKG-IN-1

PI4Kβ/PKG-IN-1 (Compound 19) is an orally active dual inhibitor targeting Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG). PI4Kβ/PKG-IN-1 exhibits potent antiplasmodial activity. PI4Kβ/PKG-IN-1 is promising for research of malaria [1].


Cat. No.: EX-A16331	Purity: >98%

	Chemical structure of PI4KβPKG-IN-1

For research only, Do not use for Human!

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CAS No.	3099010-19-9
Purity	>98%
Formula	C19H13ClFN7O
Mol Weight	409.804
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Gachuhi S, et al. Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria. J Med Chem. 2025 Jun 12;68(11):10757-10770.
CoA	CoA of PI4KβPKG-IN-1

Smiles:	FC1=CC(=CC=C1Cl)CN2N=C(C=3C=CC=4OC(=NC4C3)N)C=5C(=NC=NC52)N


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