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Product Information:

PI3Kα-IN-31

PI3Kα-IN-31 is an orally active and selective PI3Kα inhibitor. PI3Kα-IN-31 shows potent preference for mutant PI3Kα over wild-type PI3Kα. PI3Kα-IN-31 exerts antiproliferative effects in PI3Kα-mutant cancer cells. PI3Kα-IN-31 suppresses tumor growth in xenograft models. PI3Kα-IN-31 can be used for the research of breast cancer .

Cat. No.: EX-A17440    Purity: >98%
Chemical
Chemical structure of PI3Kα-IN-31


For research only, Do not use for Human!

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CAS No.3115133-30-4
Purity>98%
FormulaC29H19ClF5N5O4
Mol Weight631.937
 
 
Reference:  

[1].Zheng ZB, et al. 1,2-Dihydropyrrolo[1,2-a]pyrazine-3(4H)-one Derivatives and Their Uses, CN, CN121045188A, 2025-12-02.

CoACoA of PI3Kα-IN-31
Smiles:O=C(N)C=1C=CC=C(C1)NC(=O)C2=CC(NC(=O)C3=CC(F)=CC(=C3)C(F)(F)F)=C4N2CC(=O)NC4C5=CC(F)=CC=C5Cl

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