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Product Information:

PI3065

PI3065 a small molecule and selective inhibitor of PI 3-kinase p110δ kinase with an Ki value of 1.5nM and IC50 value of 5nM.

Cat. No.: EX-A531    Purity: >98%
Chemical
Chemical structure of PI3065


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg650In-stock
1g895In-stock
5g3650In-stock
10g6500In-stock
custom sizget quote


CAS No.955977-50-1
Purity>98%
FormulaC27H31FN6OS
Mol Weight506.638
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1].Porta et al. Targeting PI3K/Akt/mTOR signaling in cancer. Front.Oncol., 2014;4:64

[2].Ali et al. Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer. Nature, 2014;510:407
CoACoA of PI3065
Smiles:FC1=C(C2=C(NC=C2)C=C1)C1=NC(N2CCOCC2)=C2SC(CN3CCN(CC4CC4)CC3)=CC2=N1

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