Phototrexate

Phototrexate is a photoswitchable inhibitor of the human dihydrofolate reductase (DHFR). Phototrexate has antifolate and antiproliferative properties, which can be used for the research of cancer.


Cat. No.: EX-A8914	Purity: >98%

	Chemical structure of Phototrexate

For research only, Do not use for Human!

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Synonyms	(E)-azoMTX
CAS No.	2268033-83-4
Purity	>98%
Formula	C20H19N7O5
Mol Weight	437.4088

Reference:	[1]. Matera C, et al. Photoswitchable Antimetabolite for Targeted Photoactivated Chemotherapy. J Am Chem Soc. 2018 Nov 21;140(46):15764-15773.
CoA	CoA of Phototrexate

Smiles:	NC1=NC(N)=NC2=C1C=C(/N=N/C3=CC=C(C=C3)C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C2


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