Philanthotoxin 74 bis(trifluoroacetate)

Philanthotoxin 74 (PhTx 74) diTFA is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively .


Cat. No.: EX-A7240	Purity: >98%

	Chemical structure of Philanthotoxin 74 bis(trifluoroacetate)

For research only, Do not use for Human!

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Synonyms	PhTX 74 bis(trifluoroacetate)
CAS No.	401601-12-5
Purity	>98%
Formula	C26H43F3N4O5
Mol Weight	548.6386

Reference:	[1].Poulsen MH, et al. Evaluation of PhTX-74 as subtype-selective inhibitor of GluA2-containing AMPA receptors. Mol Pharmacol. 2014 Feb;85(2):261-8. [2].Kromann H, et al. Solid-phase synthesis of polyamine toxin analogues: potent and selective antagonists of Ca2+-permeable AMPA receptors. J Med Chem. 2002 Dec 19;45(26):5745-54.
CoA	CoA of Philanthotoxin 74 bis(trifluoroacetate)


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