PHI-101

Chk2 Inhibitor PHI-101 is an orally bioavailable inhibitor of checkpoint kinase 2 (chk2), with potential antineoplastic and chemopotentiating activities.


Cat. No.: EX-A7852	Purity: >98%

	Chemical structure of PHI-101

For research only, Do not use for Human!

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CAS No.	2127107-15-5
Purity	>98%
Formula	C19H19FN4O2S
Mol Weight	386.443
Color	White to yellow
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Park, Soo Jin et al. “A phase IA dose-escalation study of PHI-101, a new checkpoint kinase 2 inhibitor, for platinum-resistant recurrent ovarian cancer.” BMC cancer vol. 22,1 28. 3 Jan. 2022
CoA	CoA of PHI-101

Smiles:	C1C[C@@H](CNC1)NC(=O)C2=C(C=C(S2)C#CC3=CC(=CC=C3)F)NC(=O)N


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