PHGDH-IN-5

PHGDH-IN-5 (Compound B12) is a covalen inhibitor of PHGDH with an IC50 value of 0.29 μM. PHGDH-IN-5 can inhibit cell proliferation in cancer cell lines overexpressing PHGDH. PHGDH-IN-5 can reduce the production of serine derived from glucose in MDA-MB-468 cells.


Cat. No.: EX-A16976	Purity: >98%

	Chemical structure of PHGDH-IN-5

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	437	in_stock
250mg	745	in_stock
500mg	1192	in_stock
1g	2091	in_stock

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	17402-86-7
Purity	>98%
Formula	C8H5NO4S
Mol Weight	211.195
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Cao XY, et al. Identification of benzo[b]thiophene-1,1-dioxide derivatives as novel PHGDH covalent inhibitors. Bioorg Chem. 2024;146:107330.
CoA	CoA of PHGDH-IN-5

Smiles:	O=S1(C2=CC=CC([N+]([O-])=O)=C2C=C1)=O


		Search