Phen Green SK diacetate

Phen green SK (PGSK) diacetate (PGSK diacetate (5/6-mixture)) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. Phen green SK (PGSK) diacetate can react with a variety of metal ions, including Fe2+, Cd2+, Co2+, Ni2+, Zn2+, etc. Phen green SK (PGSK) diacetate chelates Fe2+, resulting in fluorescence quenching, which can be restored when a membrane-permeable chelator is added, thereby reflecting the changes in the intracellular chelatable iron pool. The excitation/emission maxima of Phen green SK diacetate are 507/532 nm, respectively.


Cat. No.: EX-A11881	Purity: >98%

	Chemical structure of Phen Green SK diacetate

For research only, Do not use for Human!

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CAS No.	234075-45-7
Purity	>98%
Formula	C37H21Cl2N3O8
Mol Weight	706.484
Color	Light yellow to yellow
State	solid
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -80°C, protect from light, stored under nitrogen; In solvent -20℃ 1 month;
Shipping	Shipped with dry ice.

Reference:	[1]. Petrat F, et al. Determination of the chelatable iron pool of isolated rat hepatocytes by digital fluorescence microscopy using the fluorescent probe, phen green SK. Hepatology. 1999;29(4):1171-1179. [2]. Li L, et al. NDRG1 alleviates Erastin-induced ferroptosis of hepatocellular carcinoma. BMC Cancer. 2025 Mar 21;25(1):522. [3]. Xu Z, et al. Total extracts from Abelmoschus manihot (L.) alleviate radiation-induced cardiomyocyte ferroptosis via regulating redox imbalances mediated by the NOX4/xCT/GPX4 axis. J Ethnopharmacol. 2024 Nov 15;334:118582.
CoA	CoA of Phen Green SK diacetate

Smiles:	CC(=O)OC1=C(C=C2C(=C1)OC3=CC(=C(C=C3C24C5=C(C=C(C=C5)C(=O)NC6=C7C=CC=NC7=C8C(=C6)C=CC=N8)C(=O)O4)Cl)OC(=O)C)Cl


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