Phage-derived 12/1 peptide

Phage-derived 12/1 peptide exhibits antitumor activity by targeting MDM2 and MDMX, an thus disrupt the MDM2-p53 and MDMX-p53 interaction, with IC50 of 0.15 and 1.25 μM.


Cat. No.: EX-A13616	Purity: >98%

	Chemical structure of Phage-derived 12/1 peptide

For research only, Do not use for Human!

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CAS No.	186180-20-1
Purity	>98%
Formula	C71H99N17O19S2
Mol Weight	1558.778
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Hu B, et al., Efficient p53 activation and apoptosis by simultaneous disruption of binding to MDM2 and MDMX. Cancer Res. 2007 Sep 15;67(18):8810-7.
CoA	CoA of Phage-derived 12/1 peptide

Smiles:	C([C@H](NC([C@H](CC1=CC=C(O)C=C1)NC([C@@H](NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC([C@@H](NC(=O)[C@H]3N(C([C@H](CCSC)N)=O)CCC3)CCCNC(=N)N)=O)=O)CCSC)=O)CC(O)=O)=O)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(N)=O)C(O)=O)=O)CC(C)C)=O)=O)CCC(O)=O)=O)C=4C=5C(NC4)=CC=CC5


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