PHA-408

PHA 408 (PHA-408) is a potent, selective and orally active IκB kinase-2 (IKK-2) inhibitor. PHA 408 is a powerful anti-inflammatory agent against lipopolysaccharide (LPS)- and cigarette smoke (CS)-mediated lung inflammation.


Cat. No.: EX-A12850	Purity: >98%

	Chemical structure of PHA-408

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	490	In-stock
25mg	960	In-stock
50mg	1560	In-stock
100mg	2500	In-stock
250mg	4800	In-stock
500mg	7800	In-stock

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CAS No.	503555-55-3
Purity	>98%
Formula	C29H27ClFN7O2
Mol Weight	560.022
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 50 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Rajendrasozhan S, et al. Anti-inflammatory effect of a selective IkappaB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke. Pulm Pharmacol Ther. 2010 Jun;23(3):172-81.
CoA	CoA of PHA-408

Smiles:	O=C(C1=NN(C2=CC=C(F)C=C2)C3=C1CCC4=CC=C(NC(C5=C(Cl)C=NC(N6CCN(C)CC6)=C5)=O)C=C43)N


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