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Product Information:

PF05089771

PF 05089771 is a potent, orally active and selective arylsulfonamide Nav1.7 inhibitor.

Cat. No.: EX-A3401    Purity: >98%
Chemical
Chemical structure of PF05089771


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg450In-stock
250mg750In-stock
500mg1150In-stock
1g1750In-stock
2g2900In-stock
5g5500In-stock


SynonymsPF-05089771
Synonyms 2PF 05089771
CAS No.1235403-62-9
Purity>98%
FormulaC18H12Cl2FN5O3S2
Mol Weight500.354
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Alexandrou AJ, et al. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. PLoS One. 2016 Apr 6;11(4):e0152405.

[2]. Theile JW, et al. The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently with Fast and Slow Inactivated Nav1.7 Channels. Mol Pharmacol. 2016 Nov;90(5):540-548.
CoACoA of PF05089771
Smiles:O=S(C1=CC(Cl)=C(OC2=CC=C(Cl)C=C2C3=CNN=C3N)C=C1F)(NC4=CSC=N4)=O

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