PF-07853578

PF-07853578 (Example 11) is a PNPLA3 degrader with an EC50 of 8 nM. PNPLA3 degrader-1 can be used in the study of cirrhosis and hepatocellular carcinoma.


Cat. No.: EX-A9586	Purity: >98%

	Chemical structure of PF-07853578

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
50mg	885	In-stock
100mg	1585	In-stock

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Synonyms	PNPLA3 degrader-1
Synonyms 2	PNPLA3-148M degrader
CAS No.	3036158-98-9
Purity	>98%
Formula	C16H19ClF2N2O4S
Mol Weight	408.848
Color	White to off-white
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Christopher William Am Ende, et al. Patatin-like phospholipase domain-containing protein 3 (pnpla3) modifiers. WO, WO2024084360A1. 2024-04-25
CoA	CoA of PF-07853578

Smiles:	C[C@@H]1CCN([C@H]2CN(CC(F)(F)C2)C(=O)OC2=CC=C(Cl)C=C2)S1(=O)=O


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