PF-07265028

PF-07265028 is a selective hematopoietic progenitor kinase 1 (HPK1/MAP4K1). PF-07265028 can be used in the research of cancer. PF-07265028 shows very potent cellular activity as measured by pSLP76 IC50 (17 nM) .


Cat. No.: EX-A12321	Purity: >98%

	Chemical structure of PF-07265028

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	450	In-stock
25mg	700	In-stock
50mg	985	In-stock
100mg	1300	In-stock
250mg	2450	In-stock
500mg	get quote	In-stock

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CAS No.	2736458-30-1
Purity	>98%
Formula	C26H32N8O
Mol Weight	472.5853
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture, 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Rebecca A Gallego, et al. Discovery of PF-07265028, A Selective Small Molecule Inhibitor of Hematopoietic Progenitor Kinase 1 (HPK1) for the Treatment of Cancer. J Med Chem. 2024 Dec 26;67(24):22002-22038.
CoA	CoA of PF-07265028

Smiles:	[C@H](CC)(N)C1=C2C(C(=O)N(C2)C=3N=C(C=CC3)C=4N5C(=NN4)CC[C@@H]5C)=CC(=N1)N6[C@H](C)CCC6


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