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Product Information:

PF-07220060

PF-07220060 (CDK4/6-IN-6) is a potent CDK4/CDK6 inhibitor with a Ki of 0.6 nM and 13.9 nM for CDK4/Cyclin D1 and CDK6/Cyclin D3, respectively. WO2019207463A1 (example A94)

Cat. No.: EX-A5365    Purity: >98%
Chemical
Chemical structure of PF-07220060


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg613in_stock
1g937in_stock


SynonymsCDK4/6-IN-6
CAS No.2380321-51-5
Purity>98%
FormulaC22H27ClFN5O3
Mol Weight463.933
ColorWhite to off-white
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ping Chen, et al. 2-amino-pyridine or 2-amino-pyrimidine derivatives as cyclin dependent kinase inhibitors. WO2019207463A1.

CoACoA of PF-07220060

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