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Product Information:

PF-06882961

PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor agonist (GLP-1R). WO 2019148044 (2019).

Cat. No.: EX-A3607    Purity: >98%
Chemical
Chemical structure of PF-06882961


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg300In-stock
500mg450In-stock
1g650In-stock
5g1950In-stock
10g3120In-stock
25gget quoteIn-stock


SynonymsDanuglipron
Synonyms 2PF6882961
CAS No.2230198-02-2
Purity>98%
FormulaC31H30FN5O4
Mol Weight555.5994
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Méndez, María et al. “Design, Synthesis, and Pharmacological Evaluation of Potent Positive Allosteric Modulators of the Glucagon-like Peptide-1 Receptor (GLP-1R).” Journal of medicinal chemistry vol. 63,5 (2020): 2292-2307.

[2]. Hun Jee Choe, Young Min Cho. Peptidyl and Non-Peptidyl Oral Glucagon-Like Peptide-1 Receptor Agonists. Endocrinol Metab (Seoul). 2021 Feb;36(1):22-29.

[3]. Griffith DA, et al. A small-molecule oral agonist of the human glucagon-like peptide-1 receptor. bioRxiv. 2020 Sep 30.
CoACoA of PF-06882961
Smiles:C1CO[C@@H]1CN2C3=C(C=CC(=C3)C(=O)O)N=C2CN4CCC(CC4)C5=NC(=CC=C5)OCC6=C(C=C(C=C6)C#N)F

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