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Product Information:

PF-04620110

PF-04620110 is a potent, selective and orally bioavailable diglyceride acyltransferase-1 (DGAT-1) inhibitor with an IC50 of 19 nM .

Cat. No.: EX-A10681    Purity: >98%
Chemical
Chemical structure of PF-04620110


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg909in_stock
500mg1363in_stock
1g2428in_stock
2g3607in_stock
3g4672in_stock
5g7092in_stock


CAS No.1109276-89-2
Purity>98%
FormulaC21H24N4O4
Mol Weight396.4397
Colorwhite to off-white
Statesolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Dow RL, et al. Design and synthesis of potent, orally-active DGAT-1 inhibitors containing a dioxino[2,3-d]pyrimidine core. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6122-5.

[2]. Dow RL, et al. Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1. ACS Med Chem Lett. 2011 Mar 18;2(5):407-12.

CoACoA of PF-04620110
Smiles:O=C(C[C@@H]1CC[C@H](CC1)C2=CC=C(C=C2)N3CCOC4=NC=NC(N)=C4C3=O)O

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