PF-00356231 Hydrochloride

PF-00356231 hydrochloride is a specific, non-peptidic, non-zinc chelating ligand and inhibitor of matrix metalloproteinase MMP-12 (IC50=1.4 μM). PF-00356231 hydrochloride binds to MMP-12 and forms PF-00356231/MMP-12 complex. PF-00356231 hydrochloride shows potency against MMP-13, MMP-8, MMP-9, MMP-3 with IC50s of 0.00065, 1.7, 0.98, 0.39 μM, respectively.


Cat. No.: EX-A10922	Purity: >98%

	Chemical structure of PF-00356231 Hydrochloride

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	450	In-stock
250mg	900	In-stock
500mg	1350	In-stock
1g	1980	In-stock

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CAS No.	820223-77-6
Purity	>98%
Formula	C25H21ClN2O3S
Mol Weight	464.964
Color	White to light yellow
State	Solid
Solubility	DMSO : 20.83 mg/mL H2O : < 0.1 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder 4℃, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Morales R, et al. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76.
CoA	CoA of PF-00356231 Hydrochloride

Smiles:	OC(C[C@H](C1=CC=CC=C1)NC(C2=CC(C3=CC=C(C4=CC=NC=C4)C=C3)=CS2)=O)=O.[H]Cl


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