PE154

PE154 (Compound 13) is a potent fluorescent inhibitor of human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) (IC50s=280 pM and 16 nM, respectively). PE154 can label β-amyloid plaques in histochemical analysis.


Cat. No.: EX-A7846M	Purity: >98%

	Chemical structure of PE154

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	502	in_stock
100mg	776	in_stock
250mg	1588	in_stock
500mg	2494	in_stock
1g	3941	in_stock
2g	6207	in_stock

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CAS No.	1192750-33-6
Purity	>98%
Formula	C35H35N5O4
Mol Weight	589.6835
Color	Light yellow to yellow
State	solid powder
Solubility	DMSO : 8.33 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; protect from light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Paul W Elsinghorst, et al. A gorge-spanning, high-affinity cholinesterase inhibitor to explore beta-amyloid plaques. Org Biomol Chem. 2009 Oct 7;7(19):3940-6. [2]. Davide Brambilla, et al. Nanotechnologies for Alzheimer's disease: diagnosis, therapy, and safety issues. Nanomedicine. 2011 Oct;7(5):521-40.
CoA	CoA of PE154

Smiles:	CCN(CC)C1=CC2=C(C=C1)C(=C(C(=O)O2)C=NC3=CC=C(C=C3)CC(=O)NNC4=C5CCCCC5=NC6=CC=CC=C64)O


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