PDK4-IN-2

PDK4-IN-2 (compound 8) is a pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 of 46 µM. PDK4-IN-2 improves ejection fraction of failing hearts by regulating bioenergetics via activation of the tricarboxylic acid cycle.


Cat. No.: EX-A8927	Purity: >98%

	Chemical structure of PDK4-IN-2

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock	Quantity	Order
1g	get quote	Inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	1616752-12-5
Purity	>98%
Formula	C13H10O5
Mol Weight	246.2155
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Kenichi Aizawa, et al. A Potent PDK4 Inhibitor for Treatment of Heart Failure with Reduced Ejection Fraction. Cells. 2023 Dec 30;13(1):87.
CoA	CoA of PDK4-IN-2

Smiles:	COC(C1=CC2=C(C(O)=C1)C(C=C(C2=O)C)=O)=O


		Search