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Product Information:

PD-1/PD-L1-IN-NP19

PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. PD-1/PD-L1-IN-NP19 could activate the immune microenvironment in tumor, which may contribute to its antitumor effects.

Cat. No.: EX-A7967    Purity: 98+%
Chemical
Chemical structure of PD-1/PD-L1-IN-NP19


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
25mg850In-stock
50mg1150In-stock
100mg1750In-stock
200mg2450In-stock
500mg3350In-stock
1g4850In-stock


SynonymsNP19
CAS No.2377916-66-8
Purity98+%
FormulaC33H31ClN2O4
Mol Weight555.063
ColorWhite to off-white
Statesolid powder
SolubilityDMSO : 2 mg/mL
Shelf Life>3 years if stored properly
StoragePowder   -20°C, 3 years , 4°C, 2 years ; In solvent    -20°C, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Cheng B, et, al. Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction As Potential Anticancer Agents. J Med Chem. 2020 Jul 15.

CoACoA of PD-1/PD-L1-IN-NP19

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