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Product Information:

PCSK9 inhibitor 1

PCSK9 inhibitor 1 is a highly potent proprotein convertase subtilisin-like/kexin type 9 (PCSK9) inhibitor.

Cat. No.: EX-A12774    Purity: >98%
Chemical
Chemical structure of PCSK9 inhibitor 1


For research only, Do not use for Human!

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CAS No.2867496-36-2
Purity>98%
FormulaC81H105FN15O15S2
Mol Weight1611.92
 
 
Reference:  

[1]. Kuethe, Jeffrey T et al. “Synthesis of a Complex and Highly Potent PCSK9 Inhibitor.” Organic letters vol. 25,27 (2023): 5001-5005. doi:10.1021/acs.orglett.3c01635

CoACoA of PCSK9 inhibitor 1
Smiles:FC=1C=C2C(N3C=C2C[C@]4(C(=O)N5[C@]6([C@](CC5)(OC/C=C/CC7=CC(C[C@@](C(=O)N4)(NC(=O)[C@@H](CNC(CCOCCOCC[N+](C)(C)C)=O)NC(=O)[C@H](C)NC(=O)CCSCC=8C=C(N9C=C(C3)N=N9)C=C(C8)CSCCNC(=O)[C@@]%10(C)N(C(=O)[C@H](CC%11=CC=C(OC)C=C%11)NC(=O)[C@]([C@@H](C)O)(NC6=O)[H]

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