PBX-7016

PBX-7016 is a Camptothecin derivative. PBX-7016 can selectively inhibit Topoisomerase 1. PBX-7016 can specifically bind and degrade the cancer protein DDX5, thereby down-regulating the expression of anti-apoptotic proteins such as Survivin, Mcl-1, and XIAP, and promoting the apoptosis of cancer cells. PBX-7016 can be used to synthesis of ADCs .


Cat. No.: EX-A16021	Purity: >98%

	Chemical structure of PBX-7016

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	get quote	inquire
100mg	get quote	inquire
500mg	get quote	inquire
1g	get quote	inquire
5g	get quote	inquire

Send PO to E-mail:[email protected]; or Fax:+86 020 81619670

Discount Request


CAS No.	3003834-34-9
Purity	>98%
Formula	C27H25N3O8
Mol Weight	519.5027
Color	Off-white to light yellow
State	Solid
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, sealed storage, away from moisture; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. 정두영, et al. Antibody-drug conjugate having camptothecin-based drug linked to antibody having low antigen-binding affinity through linker. WO2024049220A1. 2023-08-30
CoA	CoA of PBX-7016

Smiles:	N(C([C@@H](C)O)=O)[C@@H]1C2=C3C(=C4C(=CC3=NC5=C2CN6C5=CC7=C(C6=O)COC(=O)[C@@]7(CC)O)OCO4)CC1


		Search