PBT434 mesylate

PBT434 mesylate is a potent, orally active and cross the blood-brain barrier α-synuclein aggregation inhibitor. PBT434 mesylate can be used as a iron chelator and modulates transcellular iron trafficking.


Cat. No.: EX-A8324	Purity: >98%

	Chemical structure of PBT434 mesylate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
10mg	1100	Inquire
25mg	1900	Inquire
50mg	2900	Inquire
100mg	get quote
1g	get quote
2g	get quote

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Synonyms	ATH-434 mesylate
CAS No.	2387898-69-1
Purity	>98%
Formula	C13H17Cl2N3O5S
Mol Weight	398.262
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>1 years if stored properly
Storage	4°C, sealed storage, away from moisture
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Finkelstein DI, et al. The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease. Acta Neuropathol Commun. 2017 Jun 28;5(1):53. [2]. Bailey DK, Clark W, Kosman DJ. The iron chelator, PBT434, modulates transcellular iron trafficking in brain microvascular endothelial cells. PLoS One. 2021 Jul 26;16(7):e0254794.
CoA	CoA of PBT434 mesylate

Smiles:	O=C1C2=C(N=C(CNCC)N1C)C(O)=C(Cl)C=C2Cl.O=S(O)(C)=O


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