PB94

PB94 is a selective HDAC11 inhibitor (IC50=108 nM). PB94 can be radiolabeled as [11C]-PB94 for use in positron emission tomography (PET), as well as brain uptake and metabolic properties in administered live animals. PB94 improves neuropathic pain in mice and could be used to study neurological indications.


Cat. No.: EX-A11658	Purity: >98%

	Chemical structure of PB94

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
50mg	750	In-stock
100mg	1150	In-stock
200mg	get quote	Inquire
500mg	get quote	Inquire
1g	get quote	Inquire

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CAS No.	3032970-74-1
Purity	>98%
Formula	C29H33N3O4
Mol Weight	487.59
Color	White to off-white
State	Solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Bai P et al. Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice. J Med Chem. 2023 Nov 16.
CoA	CoA of PB94

Smiles:	COC1=C(C=CC(=C1)CN2C=CC3=C2C=CC(=C3)C(=O)NCC45CC6CC(C4)CC(C6)C5)C(=O)NO


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