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Product Information:

PARP10/15-IN-3

PARP10/15-IN-3 (Compound 8a) is a potent PARP10 and PARP15 dual inhibitor with IC50 values of 0.14 µM and 0.40 µM against PARP10 and PARP15, respectively. PARP10/15-IN-3 is able to enter cells and rescue cells from apoptosis .

Cat. No.: EX-A10535    Purity: >98%
Chemical
Chemical structure of PARP10/15-IN-3


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
500mg756In-stock
1g1320In-stock


CAS No.2892064-88-7
Purity>98%
FormulaC15H18N2O3
Mol Weight274.315
Colorwhite to off-white
Statesolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder: 4℃, sealed storage, away from moisture and light, 2 years; In solvent: -20℃, 1 month
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Nizi MG, et al. Potent 2,3-dihydrophthalazine-1,4-dione derivatives as dual inhibitors for mono-ADP-ribosyltransferases PARP10 and PARP15. Eur J Med Chem. 2022 Jul 5;237:114362.

CoACoA of PARP10/15-IN-3
Smiles:O=C1NNC(=O)C2=CC(OCC3CCCCC3)=CC=C12

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