PARP1-IN-5

PARP1-IN-5 is a low toxicity, orally active, potent and selective PARP-1 inhibitor (IC50 =14.7 nM). PARP1-IN-5 can be used for the research of cancer .


Cat. No.: EX-A5660A	Purity: >98%

	Chemical structure of PARP1-IN-5

For research only, Do not use for Human!

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CAS No.	2735645-53-9
Purity	>98%
Formula	C25H24N2O5S
Mol Weight	464.533

Reference:	[1].Long H, et al. Discovery of Novel Apigenin-Piperazine Hybrids as Potent and Selective Poly (ADP-Ribose) Polymerase-1 (PARP-1) Inhibitors for the Treatment of Cancer. J Med Chem. 2021;64(16):12089-12108.
CoA	CoA of PARP1-IN-5

Smiles:	O=C1C=C(OC2=C1C(O)=CC(O)=C2CN3CCN(CC3)CC4=CC=CS4)C5=CC=C(C=C5)O


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