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Product Information:

PAIR2

PAIR2 is a potent and selective partial antagonist of IRE1α RNase. PAIR2 can completely occupy IRE1α's ATP-binding site in cells and block the ability of a potent KIRA to inhibit XBP1 splicing.

Cat. No.: EX-A7178    Purity: >98%
Chemical
Chemical structure of PAIR2


For research only, Do not use for Human!

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50mg2250Inquire
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CAS No.2771006-54-1
Purity>98%
FormulaC27H26F4N6O3S
Mol Weight590.592
Statesolid powder
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Feldman HC, et, al. ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nat Chem Biol. 2021 Nov;17(11):1148-1156.

CoACoA of PAIR2

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