Paclitaxel Succinate

Paclitaxel-Succinic acid (paclitaxel-succinate , paclitaxel-semisucinic acid)is a paclitaxel derivative with a succinic acid linker. Paclitaxel-Succinic acid can be used to prepare paclitaxel conjugates for drug delivery and nanomedicine research.


Cat. No.: EX-A9286	Purity: >98%

	Chemical structure of Paclitaxel Succinate

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
100mg	900	Inquire
250mg	1650	Inquire
500mg	2550	Inquire
1g	get quote	Inquire

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Synonyms	Paclitaxel-Succinic acid
CAS No.	117527-50-1
Purity	>98%
Formula	C51H55NO17
Mol Weight	953.9789
State	solid
Shelf Life	>2 years if stored properly
Storage	Powder -20℃ 2 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Yan, Qunfang et al. “Construction of polymer-paclitaxel conjugate linked via a disulfide bond.” Materials science & engineering. C, Materials for biological applications vol. 58 (2016): 580-5. doi:10.1016/j.msec.2015.09.025 [2]. Yin, Shaoping et al. “Intracellular delivery and antitumor effects of a redox-responsive polymeric paclitaxel conjugate based on hyaluronic acid.” Acta biomaterialia vol. 26 (2015): 274-85. doi:10.1016/j.actbio.2015.08.029 [3]. He, XiaoCong et al. “Molecular analysis of interactions between a PAMAM dendrimer-paclitaxel conjugate and a biomembrane.” Physical chemistry chemical physics : PCCP vol. 17,44 (2015): 29507-17. doi:10.1039/c5cp02242h [4]. Wu, Di et al. “Anti-tumor activity of folate targeted biodegradable polymer-paclitaxel conjugate micelles on EMT-6 breast cancer model.” Materials science & engineering. C, Materials for biological applications vol. 53 (2015): 68-75. doi:10.1016/j.msec.2015.04.012
CoA	CoA of Paclitaxel Succinate

Smiles:	O(C(C)=O)[C@]12[C@]3([C@H](OC(=O)C4=CC=CC=C4)[C@@]5(O)C(C)(C)C([C@@H](OC(C)=O)C(=O)[C@]3(C)[C@@H](O)C[C@]1(OC2)[H])=C(C)[C@@H](OC([C@@H]([C@@H](NC(=O)C6=CC=CC=C6)C7=CC=CC=C7)OC(CCC(O)=O)=O)=O)C5)[H]


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