P5SA-2

P5SA-2 is a selective allosteric activator of PPP5C. P5SA-2 exerts its effects by modulating the phosphatase domain of PPP5C and can increase PPP5C activity by 3.2-fold at 100 μM with an apparent affinity constant of 7.8 μM. P5SA-2 can be used in cancer and Alzheimer's disease research.


Cat. No.: EX-A13472	Purity: >98%

	Chemical structure of P5SA-2

For research only, Do not use for Human!

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100mg	get quote
1g	get quote

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CAS No.	864717-20-4
Purity	>98%
Formula	C17H15ClN2O3
Mol Weight	330.766
Color	Off-white to light yellow
State	Solid
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, protect from light; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Zhang H, et al. Dual function of protein phosphatase 5 (PPP5C): An emerging therapeutic target for drug discovery. Eur J Med Chem. 2023 Jun 5;254:115350.
CoA	CoA of P5SA-2

Smiles:	ClC1=CC=C(C=C1)CC2=NOC(=N2)C=3C=CC(OC)=C(OC)C3


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