P-3FAX-Neu5Ac

3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X.


Cat. No.: EX-A10650	Purity: >98%

	Chemical structure of P-3FAX-Neu5Ac

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
25mg	950	In-stock
50mg	1550	In-stock
100mg	2585	In-stock

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Synonyms	3FAx-Neu5Ac
CAS No.	117405-58-0
Purity	>98%
Formula	C22H30FNO14
Mol Weight	551.4703
Color	white to off-white
State	solid
Solubility	Soluble in DMSO
Shelf Life	>3 years if stored properly
Storage	Powder -20℃, 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Cory D Rillahan, et al. Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome. Nat Chem Biol. 2012 Jul;8(7):661-8. [2]. Natoni A, et al. Inhibition of Sialylation Impairs Adhesion on Madcam-1 and E-Selectin and Sensitize Multiple Myeloma Cells to Bortezomib in a Xenograft Mouse Model. Blood, 2018, 132: 3204.
CoA	CoA of P-3FAX-Neu5Ac

Smiles:	COC([C@]1(O[C@@]([C@H](NC(C)=O)[C@@H](OC(C)=O)[C@H]1F)([H])[C@H](OC(C)=O)[C@H](OC(C)=O)COC(C)=O)OC(C)=O)=O


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