OXA 06 dihydrochloride

OXA-06 hydrochloride is an ATP-competitive ROCK inhibitor that blocks anchorage-dependent growth and invasion of non-small cell lung cancer cell lines. OXA-06 hydrochloride inhibits cofilin phosphorylation but does not stimulate apoptosis .


Cat. No.: EX-A8080	Purity: >98%

	Chemical structure of OXA 06 dihydrochloride

For research only, Do not use for Human!

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CAS No.	1825455-91-1
Purity	>98%
Formula	C21H20Cl2FN3
Mol Weight	404.308
Color	White to off-white
State	solid powder
Solubility	DMSO : 25 mg/mL
Shelf Life	>1 years if stored properly
Storage	4°C, sealed storage, away from moisture and light
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Vigil D, et al. ROCK1 and ROCK2 are required for non-small cell lung cancer anchorage-independent growth and invasion. Cancer Res. 2012 Oct 15;72(20):5338-47.
CoA	CoA of OXA 06 dihydrochloride

Smiles:	C1=CC=C(C(=C1)CNCC2=CC=C(C=C2)C3=C4C=CNC4=NC=C3)F.Cl.Cl


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