Oteseconazole

Oteseconazole (VT-1161) is an orally active anti-fungal agent, potently binds to and inhibits Candida albicans CYP51 (Kd, <39 nM), shows no obvious effect on human CYP51.


Cat. No.: EX-A8008	Purity: >98%

	Chemical structure of Oteseconazole

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	594	in_stock
1g	1107	in_stock
5g	3938	inquire

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Synonyms	VT-1161
CAS No.	1340593-59-0
Purity	>98%
Formula	C23H16F7N5O2
Mol Weight	527.3943
Color	White to off-white
State	solid powder
Solubility	DMSO : 175 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Warrilow AG, et al. The clinical candidate VT-1161 is a highly potent inhibitor of Candida albicans CYP51 but fails to bind the human enzyme. Antimicrob Agents Chemother. 2014 Dec;58(12):7121-7. [2]. Garvey EP, et al. VT-1161 dosed once daily or once weekly exhibits potent efficacy in treatment of dermatophytosis in a guinea pig model. Antimicrob Agents Chemother. 2015 Apr;59(4):1992-7.
CoA	CoA of Oteseconazole

Smiles:	O[C@@](CN1C=NN=N1)(C(C=CC(F)=C2)=C2F)C(F)(C3=CC=C(C4=CC=C(OCC(F)(F)F)C=C4)C=N3)F


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