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Product Information:

OSI-420

Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor.

Cat. No.: EX-A064-1    Purity: 99%+
Chemical
Chemical structure of OSI-420


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg685In-stock
200mg1085In-stock
500mg1585In-stock


SynonymsDesmethyl Erlotinib (CP-473420) HCl
Synonyms 2(183320-51-6 HCl)
CAS No.183321-86-0
Purity99%+
FormulaC21H21N3O4
Mol Weight379.4091
Statesolid powder
SolubilitySoluble in DMSO
Shelf Life>2 years if stored properly
StoragePowder -20℃ 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Thappali SR, et al. Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation.Sci Pharm. 2012 Jul-Sep;80(3):633-46.
CoACoA of OSI-420
Smiles:COCCOC1=C(OCCO)C=C2C(NC3=CC=CC(=C3)C#C)=NC=NC2=C1

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