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Product Information:

Orsellinic acid

Orsellinic acid is a Benzoic acid (HY-N0216) derivative. Orsellinic acid can be isolated from Chaetomium globosum endophytic on Ephedra fasciculata (Mormon tea). Orsellinic acid blocks PAF-mediated Apoptosis, inhibits caspase-3/7 activation, and PARP cleavage. Orsellinic acid can be used in research of neurons and various tumors (non-small cell lung cancer, breast cancer, neuroblastoma, pancreatic cancer) .

Cat. No.: EX-A16369    Purity: >98%
Chemical
Chemical structure of Orsellinic acid


For research only, Do not use for Human!

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CAS No.480-64-8
Purity>98%
FormulaC8H8O4
Mol Weight168.1467
ColorLight yellow to yellow
StateSolid
Solubilitysoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4℃, protect from light; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Lopes TI, et al. Radical-scavenging activity of orsellinates. Chem Pharm Bull (Tokyo). 2008;56(11):1551-1554.

[2].Bashyal BP, et al. Globosumones A-C, cytotoxic orsellinic acid esters from the Sonoran desert endophytic fungus Chaetomium globosum. J Nat Prod. 2005 May;68(5):724-8.

p> [3].Ryan SD, et al. Platelet activating factor-induced neuronal apoptosis is initiated independently of its G-protein coupled PAF receptor and is inhibited by the benzoate orsellinic acid. J Neurochem. 2007 Oct;103(1):88-97.

CoACoA of Orsellinic acid
Smiles:O=C(O)C=1C(O)=CC(O)=CC1C

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