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Product Information:

ORIC-533

ORIC-533 is an orally active, selective CD73 inhibitor with AMP-competition. ORIC-533 restores immunosuppressed CD8+ T cell proliferation and activation, triggers significant lysis and cell death of multiple myeloma cells in the bone marrow microenvironment.

Cat. No.: EX-A8749    Purity: >98%
Chemical
Chemical structure of ORIC-533


For research only, Do not use for Human!

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CAS No.2641306-62-7
Purity>98%
FormulaC20H29ClN9O9P
Mol Weight605.926
 
 
Reference:  

[1]. Junttila M R, et al., ORIC-533, a small molecule CD73 inhibitor with best-in-class properties, reversesimmunosuppression and has potential as an immunomodulatory therapy in patients with multiple myeloma[J]. Cancer Research, 2022, 82(12_Supplement): 2074-2074.

CoACoA of ORIC-533

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