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Product Information:

OP-0595

Nacubactam is a potent inhibitor of non-β-lactam-β-lactamase with activity against class A and class C β-lactamases.

Cat. No.: EX-A5376    Purity: >98%
Chemical
Chemical structure of OP-0595


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
50mg650In-stock
100mg850In-stock
250mg1050In-stock
500mg1550In-stock
1g2650In-stock
5g10600In-stock


SynonymsNacubactam
CAS No.1452458-86-4
Purity>98%
FormulaC9H16N4O7S
Mol Weight324.311
ColorWhite to light brown
Statesolid powder
SolubilitySoluble in DMSO 100 mg/mL H2O 50 mg/mL
Shelf Life>2 years if stored properly
StoragePowder -20°C, protect from light, stored under nitrogen; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  [1]. Monogue ML, et al. In Vivo Efficacy of Meropenem with a Novel Non-β-Lactam-β-Lactamase Inhibitor, Nacubactam, against Gram-Negative Organisms Exhibiting Various Resistance Mechanisms in a Murine Complicated Urinary Tract Infection Model. Antimicrob Agents Chemother. 2018 Aug 27;62(9).

[2]. Livermore DM, et al. Activity of OP0595/β-lactam combinations against Gram-negative bacteria with extended-spectrum, AmpC and carbapenem-hydrolysing β-lactamases. J Antimicrob Chemother. 2015 Nov;70(11):3032-41.
CoACoA of OP-0595

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