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Product Information:

Onzotrigine

Onzotrigine (LTG-001) is a potent, selective, voltage-gated sodium channel Nav1.8 inhibitor. Onzotrigine may be used in pain-related research .

Cat. No.: EX-A17442    Purity: >98%
Chemical
Chemical structure of Onzotrigine


For research only, Do not use for Human!

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SynonymsLTG-001
CAS No.2834099-10-2
Purity>98%
FormulaC21H18F4N4O3S
Mol Weight482.451
 
 
Reference:  

[1].Singla N, et al. Phase 2b Trial of a NaV1.8 Inhibitor for Acute Pain. N Engl J Med. 2026 Jul 30;395(5):454-464.

CoACoA of Onzotrigine
Smiles:C(NC1=CC(S(C)(=N)=O)=CC=C1)(=O)C2=C(OC3=C(C)N=C(F)C=C3)N=CC(C(F)(F)F)=C2C

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