Onc112

Onc112 is a proline-rich antimicrobial peptide that displays potent activity against Gram-negative bacteria. Onc112 inhibits translation by blocking and destabilizing the initiation complex.


Cat. No.: EX-A13591	Purity: >98%

	Chemical structure of Onc112

For research only, Do not use for Human!

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CAS No.	1273548-87-0
Purity	>98%
Formula	C109H177N37O24
Mol Weight	2389.8052
Color	White to off-white
State	Solid
Solubility	H2O : ? 50 mg/mL
Shelf Life	>2 years if stored properly
Storage	Powder 80°C, 2 years , -20°C, 1 year, Sealed storage, away from moisture; In solvent -20°C, 1 month.
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Seefeldt AC, et al. The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex. Nat Struct Mol Biol. 2015 Jun;22(6):470-5.
CoA	CoA of Onc112

Smiles:	C(=O)([C@H]1N(C([C@@H](NC(=O)[C@H]2N(C([C@@H](NC(=O)[C@H]3N(C([C@@H](NC([C@@H](NC(=O)[C@H]4N(C(=O)[C@H]5N(C([C@@H](NC([C@@H](NC([C@H](C(C)C)N)=O)CC(O)=O)=O)CCCCN)=O)CCC5)CCC4)CC6=CC=C(O)C=C6)=O)CC(C)C)=O)CCC3)CCCNC(=N)N)=O)CCC2)CCCNC(=N)N)=O)CCC1)N7[C@H](


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