OICR-8268

OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs[1].


Cat. No.: EX-A17133	Purity: >98%

	Chemical structure of OICR-8268

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
5mg	485	in-stock
10mg	685	in-stock
25mg	1285	in-stock
50mg	1985	in-stock
100mg	2985	in-stock
500mg	get quote	in-stock

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CAS No.	3000549-26-5
Purity	>98%
Formula	C19H14Cl2F2N4O2
Mol Weight	439.243
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, 3 years , 4°C, 2 years ; In solvent -20°C, 1 month
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1].Alice Shi Ming Li, et al. Discovery of Nanomolar DCAF1 Small Molecule Ligands. J Med Chem. 2023 Apr 13;66(7):5041-5060.
CoA	CoA of OICR-8268

Smiles:	O=C(C1=CNN=C1C2=CC=C(Cl)C=C2F)N[C@H](C3=CC=C(F)C(Cl)=C3)CC(N)=O


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