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Product Information:

OGT2115

OGT 2115 is a potent, cell-permeable and orally active heparanase inhibitor with an IC50 of 0.4 μM. OGT 2115 has anti-angiogenic properties (IC50 of 1 μM). OGT 2115 also inhibits heparan sulfate degradation activity.

Cat. No.: EX-A11309    Purity: >98%
Chemical
Chemical structure of OGT2115


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
250mg865In-stock
500mg1255In-stock
1g1760In-stock


CAS No.853929-59-6
Purity>98%
FormulaC24H16BrFN2O4
Mol Weight495.297
ColorWhite to yellow
Statesolid
SolubilityDMSO : 10 mg/mL
Shelf Life>3 years if stored properly
StoragePowder -20℃ 3 years; 4℃, 2 years; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. [1]Courtney SM, et al. Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor. Bioorg Med Chem Lett. 2005 May 2;15(9):2295-9.

[2]. Li Y, et al. Suppression of endoplasmic reticulum stress-induced invasion and migration of breast cancer cells through the downregulation of heparanase. Int J Mol Med. 2013 May;31(5):1234-42.

CoACoA of OGT2115
Smiles:C1=CC(=CC=C1/C=C/C(=O)NC2=C(C=C(C=C2)C3=NC4=C(O3)C=CC(=C4)CC(=O)O)F)Br

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