Inhibitor Specialist 
Product Information:
| Cat. No.: EX-A5384 | Purity: >98% |
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| Chemical structure of Odevixibat |
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| Synonyms | A4250 |
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| CAS No. | 501692-44-0 |
| Purity | >98% |
| Formula | C37H48N4O8S2 |
| Mol Weight | 740.929 |
| Color | White to off-white |
| State | solid powder |
| Solubility | Soluble in DMSO 166.67 mg/mL |
| Shelf Life | >2 years if stored properly |
| Storage | Powder -20°C, stored under nitrogen; In solvent -20℃ 1 month; |
| Shipping | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| Reference: | [1]. Baghdasaryan A, Fuchs CD, Österreicher CH, Lemberger UJ, Halilbasic E, Påhlman I, Graffner H, Krones E, Fickert P, Wahlström A, Ståhlman M, Paumgartner G, Marschall HU, Trauner M. Inhibition of intestinal bile acid absorption improves cholestatic liver and bile duct injury in a mouse model of sclerosing cholangitis. J Hepatol. 2016 Mar;64(3):674-81. doi: 10.1016/j.jhep.2015.10.024. Epub 2015 Oct 31. PMID: 26529078.
[2]. Graffner H, Gillberg PG, Rikner L, Marschall HU. The ileal bile acid transporter inhibitor A4250 decreases serum bile acids by interrupting the enterohepatic circulation. Aliment Pharmacol Ther. 2016 Jan;43(2):303-10. doi: 10.1111/apt.13457. Epub 2015 Nov 2. PMID: 26527417. |
| CoA | CoA of Odevixibat |
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