OATD01

OATD-01 is a highly potent, first-in-class, orally active and selective chitinase inhibitor with low nanomolar activity toward CHIT1 (hCHIT1,IC50=23 nM). OATD-01 shows excellect PK profile in multiple species and is selectivity against a panel of other off-targets. OATD-01 exhibits significant antifibrotic efficacy in vivo and can be used for pulmonary fibrosis (IPF) research.


Cat. No.: EX-A5697	Purity: >98%

	Chemical structure of OATD01

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
500mg	2250	In-stock
1g	3600	In-stock
5g	get quote

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Synonyms	OATD-01
CAS No.	2088453-21-6
Purity	>98%
Formula	C19H27ClN6O
Mol Weight	390.91
Color	white to off-white
State	solid powder
Solubility	Soluble in DMSO 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20°C, protect from light, stored under nitrogen, 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Robert Koralewski, et al. Discovery of OATD-01, a First-in-Class Chitinase Inhibitor as Potential New Therapeutics for Idiopathic Pulmonary Fibrosis. J Med Chem. 2020 Dec 24;63(24):15527-15540.
CoA	CoA of OATD01


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