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Product Information:

O-Me Eribulin

O-Me Eribulin is a derivative of Eribulin and is an ADC cytotoxin that can be used for ADC synthesis. O-Me Eribulin can inhibit the cell viability of SKBR3, MDA-MB-468, and A549 cells, with IC50 values of 0.2052, 0.1827, and 0.5151 nM, respectively. O-Me Eribulin can be used for tumor research.

Cat. No.: EX-A13371    Purity: >98%
Chemical
Chemical structure of O-Me Eribulin


For research only, Do not use for Human!

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CAS No.2676196-81-7
Purity>98%
FormulaC41H61NO11
Mol Weight743.9231
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Sun xing, et al. Drug conjugate of eribulin derivative. CN2022/107479. 2023-01-26.

CoACoA of O-Me Eribulin
Smiles:C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](OC)CN)[C@@H]9OC)([H])[C@]9([H])CC5=O

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