NVL-655

Neladalkib (NVL-655, ALK-IN-27) is a potent ALK inhibitor. ALK-IN-27 shows antitumor activity. ALK-IN-27 has an IC50 of 2.7 nM for Ba/F3 CLIP1-LTK cell.


Cat. No.: EX-A8218	Purity: >99%

	Chemical structure of NVL-655

For research only, Do not use for Human!

Size	Unit Price (US$)	Stock
250mg	250	In-stock
500mg	425	In-stock
1g	750	In-stock
5g	2500	In-stock
10g	4372	In-stock

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Synonyms	NVL655
Synonyms 2	Neladalkib
CAS No.	2739866-40-9
Purity	>99%
Formula	C23H22ClFN6O
Mol Weight	452.912
Color	White to off-white
State	solid powder
Solubility	DMSO : 100 mg/mL
Shelf Life	>3 years if stored properly
Storage	Powder -20℃ 3 years; In solvent -20℃ 1 month;
Shipping	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Reference:	[1]. Jennifer Anne Green, et al. Methods of treating solid tumor using (19r)-5-chloro-3-ethyl-16-fluoro-10,19-dimethyl-20-oxa-3,4,10,11,23-pentaazapentacyclo[19.3.1.02,6.08,12.013,18]pentacosa-1(24),2(6),4,8,11,13,15,17,21(25),22-decaen-22-amine. WO2023196910A1.
Data Sheet	Data sheet of NVL-655
CoA	CoA of NVL-655
SDS	SDS of NVL-655

Smiles:	CCN1C2=C(C(Cl)=N1)CC3=CN(C)N=C3C4=CC=C(F)C=C4[C@H](OC5=C(N)N=CC2=C5)C


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