background


Product Information:

Nusinersen

Nusinersen is an antisense oligonucleotide compound that modifies pre-messenger RNA splicing of the SMN2 gene, thereby promoting full-length SMN protein production.

Cat. No.: EX-A8111    Purity: >97%
Chemical
Chemical structure of Nusinersen


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
5mg1250In-stock
10mg2150In-stock
25mg3550In-stock
50mgget quoteIn-stock
100mgget quoteIn-stock


CAS No.1258984-36-9
Purity>97%
FormulaC234H340N61O128P17S17
Mol Weight7127.194
ColorWhite to off-white
Statesolid powder
Storage

-20℃, stored under nitrogen, away from moisture

In solvent : -80℃, 6 months; -20℃, 1 month (stored under nitrogen, away from moisture)

ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Li, Qing. “Nusinersen as a Therapeutic Agent for Spinal Muscular Atrophy.” Yonsei medical journal vol. 61,4 (2020): 273-283. doi:10.3349/ymj.2020.61.4.273

[2]. Claborn, Melanie K et al. “Nusinersen: A Treatment for Spinal Muscular Atrophy.” The Annals of pharmacotherapy vol. 53,1 (2019): 61-69. doi:10.1177/1060028018789956

[3]. Mercuri, Eugenio et al. “Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy.” The New England journal of medicine vol. 378,7 (2018): 625-635. doi:10.1056/NEJMoa1710504

[4]. Finkel, Richard S et al. “Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.” The New England journal of medicine vol. 377,18 (2017): 1723-1732. doi:10.1056/NEJMoa1702752

[5]. Chiriboga, Claudia A. “Nusinersen for the treatment of spinal muscular atrophy.” Expert review of neurotherapeutics vol. 17,10 (2017): 955-962. doi:10.1080/14737175.2017.1364159

CoACoA of Nusinersen

KEYWORDS: buy Nusinersen | Nusinersen supplier | purchase | cost | manufacturer | order | distributor | buy 1258984-36-9 | 1258984-36-9 supplier