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Product Information:

NSC 693868

NSC693868 is a selective inhibitor of CDK1 and CDK5 with IC50s of 600 nM and 400 nM, respectively. NSC693868 less potently inhibits GSK3β with an IC50 of 1 µM) and does not block CDC25 activity. NSC693868 is used to help define the roles of CDK1 and CDK5 in various signaling pathways .

Cat. No.: EX-A10888    Purity: >98%
Chemical
Chemical structure of NSC 693868


For research only, Do not use for Human!

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CAS No.40254-90-8
Purity>98%
FormulaC9H7N5
Mol Weight185.1854
ColorOrange to red
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder -20°C, protect from light, stored under nitrogen; In solvent -20℃, 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1]. Ortega MA, et al. Pyrazolo[3,4-b]quinoxalines. A new class of cyclin-dependent kinases inhibitors. Bioorg Med Chem. 2002 Jul;10(7):2177-84.

CoACoA of NSC 693868
Smiles:NC1=NNC2=NC3=CC=CC=C3N=C21

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