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Product Information:

NS2B/NS3-IN-3 hydrochloride

NS2B/NS3-IN-3 hydrochloride is an inhibitor of Flavivirus NS2B-NS3 protease, with an IC50 of 0.32 μM against Zika virus NS2B-NS3 protease. NS2B/NS3-IN-3 hydrochloride also exhibits inhibitory effects on dengue virus type 2 NS2B-NS3 protease and West Nile virus NS2B-NS3 protease. NS2B/NS3-IN-3 hydrochloride inhibits the intracellular replication of Zika virus. NS2B/NS3-IN-3 hydrochloride can be used in studies related to flavivirus infections .

Cat. No.: EX-A17520    Purity: >98%
Chemical
Chemical structure of NS2B/NS3-IN-3 hydrochloride


For research only, Do not use for Human!

SizeUnit Price (US$)StockQuantityOrder
100mg393in_stock
250mg787in_stock
500mg1220in_stock
1g1951in_stock
2g3115in_stock
3g3794in_stock


CAS No.2832876-91-0
Purity>98%
FormulaC19H22ClN3O2
Mol Weight359.85
ColorOrange to red
StateSolid
SolubilitySoluble in DMSO
Shelf Life>3 years if stored properly
StoragePowder 4°C, protect from light, stored under nitrogen; In solvent -20℃ 1 month;
ShippingShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
 
 
Reference:  

[1].Nie S, et al. Synthesis, structure-activity relationship and antiviral activity of indole-containing inhibitors of Flavivirus NS2B-NS3 protease. European journal of medicinal chemistry. 2021 Dec 05;225:113767.

CoACoA of NS2B/NS3-IN-3 hydrochloride
Smiles:O=C(C1=CC2=CC=C(C=C2N1)C3=COC=C3)NCC4CCNCC4.[H]Cl

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